Friday, July 11, 2008

The Endocrine System

The endocrine system is an integrated system of small organs that involve the release of extracellular signaling molecules known as hormones. The endocrine system is instrumental in regulating metabolism, growth, development and puberty, tissue function, and also plays a part in determining mood. The field of medicine that deals with disorders of endocrine glands is endocrinology, a branch of the wider field of internal medicine.
In addition to the integrative action of the nervous system, control of various body functions is exerted by the endocrine glands. An important part of this system, the pituitary, lies at the base of the brain.


This master gland secretes a variety of hormones, including the following:
(1)
a hormone that stimulates the thyroid gland and controls its secretion of thyroxine, which dictates the rate at which all cells utilize oxygen;
(2) a hormone that controls the secretion in the adrenal gland of hormones that influence
the metabolism of carbohydrates, sodium, and potassium and control the rate at which substances are exchanged between blood and tissue fluid;
(3) substances that control the secretion in the ovaries of estrogen and progesterone
and the creation in the testicles of testosterone;
(4) the somatotropic, or growth, hormone, which controls the rate of development of
the skeleton and large interior organs through its effect on the metabolism of
proteins and carbohydrates;
(5) an insulin inhibitor—a lack of insulin causes diabetes mellitus.

The posterior lobe of the pituitary secretes vasopressin, which acts on the kidney to control the volume of urine; a lack of vasopressin causes diabetes insipidus, which results in the passing of large volumes of urine.
The posterior lobe also elaborates oxytocin, which causes contraction of smooth muscle in the intestines and small arteries and is used to bring about contractions of the uterus in childbirth.

Other glands in the endocrine system are the pancreas, which secretes insulin, and the parathyroid, which secretes a hormone that regulates the quantity of calcium and phosphorus in the blood.
source: wiki/encarta encyclopedia

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